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ChemicalBook >> CAS DataBase List >> SC-51089

SC-51089

SC-51089 price.
  • $26 - $1686.3
  • Product name: SC-51089
  • CAS: 146033-02-5
  • MF: C22H19ClN4O3
  • MW: 422.86
  • EINECS:
  • MDL Number:MFCD00869867
  • Synonyms:SC-51089;8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic Acid 2-[1-Oxo-3-(4-pyridinyl)propyl]hydrazide Hydrochloride;8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid 2-[1-oxo-3-(4-pyridinyl)propyl]hydrazide monohydrochloride;8-Chlorodibenz(Z)[b,f][1,4]oxazepine-10(11H)-carboxylicacid2-[1-oxo-3-(4-pyridinyl)propyl]hydrazidehydrochloride;SC-51089 HCl;Dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-[1-oxo-3-(4-pyridinyl)propyl]hydrazide, hydrochloride (1:1);SC-51089, EP1 receptor antagonist;2-chloro-N'-(3-(pyridin-4-yl)propanoyl)dibenzo[b,f][1,4]oxazepine-10(11H)-carbohydrazide hydrochloride
Price31 Properties Safety Information Description
31 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • AvaChem
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Thermo Scientific Chemicals
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 5mg
  • 50
  • 10mg
  • 25mg
  • 50mg
  • 100MG
  • Manufactureraablocks
  • Product numberAA001DJM
  • Product description8-chloro-N'-(3-(pyridin-4-yl)propanoyl)dibenzo[b,f][1,4]oxazepine-10(11H)-carbohydrazide hydrochloride ≥95%
  • Packaging1mg
  • Price$26
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001DJM
  • Product description8-chloro-N'-(3-(pyridin-4-yl)propanoyl)dibenzo[b,f][1,4]oxazepine-10(11H)-carbohydrazide hydrochloride ≥95%
  • Packaging5mg
  • Price$70
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001DJM
  • Product description8-chloro-N'-(3-(pyridin-4-yl)propanoyl)dibenzo[b,f][1,4]oxazepine-10(11H)-carbohydrazide hydrochloride ≥95%
  • Packaging10mg
  • Price$125
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001DJM
  • Product description8-chloro-N'-(3-(pyridin-4-yl)propanoyl)dibenzo[b,f][1,4]oxazepine-10(11H)-carbohydrazide hydrochloride ≥95%
  • Packaging25mg
  • Price$279
  • Updated2026-05-28
  • Buy
  • ManufacturerAK Scientific
  • Product number1508AH
  • Product description8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylicacid2-[1-oxo-3-(4-pyridinyl)propyl]hydrazidehydrochloride
  • Packaging1mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007807
  • Product descriptionSC-51089 95.00%
  • Packaging100MG
  • Price$1686.3
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007807
  • Product descriptionSC-51089 95.00%
  • Packaging10MG
  • Price$716.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007807
  • Product descriptionSC-51089 95.00%
  • Packaging1MG
  • Price$141.75
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7496
  • Product descriptionSC 51089
  • Packaging10mg
  • Price$155
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7496
  • Product descriptionSC 51089
  • Packaging5mg
  • Price$90
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7496
  • Product descriptionSC 51089
  • Packaging1mg
  • Price$50
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7496
  • Product descriptionSC 51089
  • Packaging25mg
  • Price$350
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7496
  • Product descriptionSC 51089
  • Packaging50mg
  • Price$1190
  • Updated2026-05-06
  • Buy
  • ManufacturerAvaChem
  • Product number6773
  • Product descriptionSC-51089 98%
  • Packaging5mg
  • Price$55
  • Updated2026-05-22
  • Buy
  • ManufacturerAvaChem
  • Product number6773
  • Product descriptionSC-51089 98%
  • Packaging25mg
  • Price$220
  • Updated2026-05-22
  • Buy
  • ManufacturerBiosynth
  • Product numberFS27799
  • Product descriptionSC 51089
  • Packaging5mg
  • Price$269.85
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA001DJM 8-chloro-N'-(3-(pyridin-4-yl)propanoyl)dibenzo[b,f][1,4]oxazepine-10(11H)-carbohydrazide hydrochloride ≥95% 1mg $26 2026-05-28 Buy
aablocks AA001DJM 8-chloro-N'-(3-(pyridin-4-yl)propanoyl)dibenzo[b,f][1,4]oxazepine-10(11H)-carbohydrazide hydrochloride ≥95% 5mg $70 2026-05-28 Buy
aablocks AA001DJM 8-chloro-N'-(3-(pyridin-4-yl)propanoyl)dibenzo[b,f][1,4]oxazepine-10(11H)-carbohydrazide hydrochloride ≥95% 10mg $125 2026-05-28 Buy
aablocks AA001DJM 8-chloro-N'-(3-(pyridin-4-yl)propanoyl)dibenzo[b,f][1,4]oxazepine-10(11H)-carbohydrazide hydrochloride ≥95% 25mg $279 2026-05-28 Buy
AK Scientific 1508AH 8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylicacid2-[1-oxo-3-(4-pyridinyl)propyl]hydrazidehydrochloride 1mg $120 2021-12-16 Buy
American Custom Chemicals Corporation API0007807 SC-51089 95.00% 100MG $1686.3 2021-12-16 Buy
American Custom Chemicals Corporation API0007807 SC-51089 95.00% 10MG $716.1 2021-12-16 Buy
American Custom Chemicals Corporation API0007807 SC-51089 95.00% 1MG $141.75 2021-12-16 Buy
ApexBio Technology B7496 SC 51089 10mg $155 2026-05-06 Buy
ApexBio Technology B7496 SC 51089 5mg $90 2026-05-06 Buy
ApexBio Technology B7496 SC 51089 1mg $50 2026-05-06 Buy
ApexBio Technology B7496 SC 51089 25mg $350 2026-05-06 Buy
ApexBio Technology B7496 SC 51089 50mg $1190 2026-05-06 Buy
AvaChem 6773 SC-51089 98% 5mg $55 2026-05-22 Buy
AvaChem 6773 SC-51089 98% 25mg $220 2026-05-22 Buy
Biosynth FS27799 SC 51089 5mg $269.85 2026-06-04 Buy
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Properties

Melting point :162-164°C
storage temp. :Store at -20°C
solubility :Soluble in DMSO (25 mg/ml) or water (25 mg/mL)
form :White solid.
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

SC-51089 is a selective antagonist of prostaglandin E2, which displays specificity towards the EP1 receptor subtype. Studies indicate that SC-51089 can induce nociceptive behaviors in rats as a result of its antagonistic effects on prostaglandin E2. This compound contains a diacylhydrazine moiety, which has often been observed to release hydrazine. Alternate studies suggest that SC-51089 can be metabolized by rat and human hepatocytes, however different metabolic products are produced. For instance, SC-51089 undergoes aromatic hydroxylation with consequent glucuronidation and sulphation in human hepatocytes, while oxidative N-dealkylation with opening of the oxazepine ring and consequent glucuronidation in observed in rat hepatocytes. SC-51089 is an inhibitor of EP2 and EP3.

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Suppliers and manufacturers

J & K SCIENTIFIC LTD. 3B Pharmachem (Wuhan) International Co.,Ltd. Chemsky（shanghai）International Co.,Ltd. EMMX Biotechnology LLC Shanghai EFE Biological Technology Co., Ltd. Shenzhen Polymeri Biochemical Technology Co., Ltd. TargetMol Chemicals Inc. ChemeGen(Shanghai) Biotechnology Co.,Ltd. Energy Chemical Nantong Hi-Future Biotechnology Co., Ltd