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ChemicalBook >> CAS DataBase List >> Sacubitril Impurity 7

Sacubitril Impurity 7

Sacubitril Impurity 7 price.
  • $21 - $2700
  • Product name: Sacubitril Impurity 7
  • CAS: 149709-44-4
  • MF: C22H25NO5
  • MW: 383.44
  • EINECS:
  • MDL Number:MFCD00921225
  • Synonyms:LBQ657;Sacubitrilat;(2R,4S)-4-(3-carboxypropanoylamino)-2-methyl-5-(4-phenylphenyl)pentanoic acid;LCZ696-4;Diacid of Sacubitril;LCZ-696 Impurity 1;Sacubitrilat (LBQ-657);Sacubitril Desethyl Impurity
Price31 Properties Safety Information Description
31 prices
Selected condition：
Brand
  • AK Scientific
  • Alichem
  • Ambeed
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1mg
  • 2mg
  • 2.5mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number7499CR
  • Product descriptionSacubitrilat
  • Packaging50mg
  • Price$184
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number149709444
  • Product description(2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoicacid
  • Packaging100mg
  • Price$338.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number149709444
  • Product description(2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoicacid
  • Packaging250mg
  • Price$574.08
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number149709444
  • Product description(2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoicacid
  • Packaging1g
  • Price$1407.6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA145106
  • Product descriptionSacubitrilat 97%
  • Packaging1mg
  • Price$21
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA145106
  • Product descriptionSacubitrilat 97%
  • Packaging5mg
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA145106
  • Product descriptionSacubitrilat 97%
  • Packaging10mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA145106
  • Product descriptionSacubitrilat 97%
  • Packaging25mg
  • Price$71
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA145106
  • Product descriptionSacubitrilat 97%
  • Packaging50mg
  • Price$92
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA145106
  • Product descriptionSacubitrilat 97%
  • Packaging100mg
  • Price$129
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA145106
  • Product descriptionSacubitrilat 97%
  • Packaging250mg
  • Price$255
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA145106
  • Product descriptionSacubitrilat 97%
  • Packaging1g
  • Price$642
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19829
  • Product descriptionLBQ657 ≥98%
  • Packaging1mg
  • Price$33
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19829
  • Product descriptionLBQ657 ≥98%
  • Packaging5mg
  • Price$131
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19829
  • Product descriptionLBQ657 ≥98%
  • Packaging10mg
  • Price$245
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19829
  • Product descriptionLBQ657 ≥98%
  • Packaging25mg
  • Price$894
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 7499CR Sacubitrilat 50mg $184 2021-12-16 Buy
Alichem 149709444 (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoicacid 100mg $338.1 2021-12-16 Buy
Alichem 149709444 (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoicacid 250mg $574.08 2021-12-16 Buy
Alichem 149709444 (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoicacid 1g $1407.6 2021-12-16 Buy
Ambeed A145106 Sacubitrilat 97% 1mg $21 2021-12-16 Buy
Ambeed A145106 Sacubitrilat 97% 5mg $42 2021-12-16 Buy
Ambeed A145106 Sacubitrilat 97% 10mg $55 2021-12-16 Buy
Ambeed A145106 Sacubitrilat 97% 25mg $71 2021-12-16 Buy
Ambeed A145106 Sacubitrilat 97% 50mg $92 2021-12-16 Buy
Ambeed A145106 Sacubitrilat 97% 100mg $129 2021-12-16 Buy
Ambeed A145106 Sacubitrilat 97% 250mg $255 2021-12-16 Buy
Ambeed A145106 Sacubitrilat 97% 1g $642 2021-12-16 Buy
Cayman Chemical 19829 LBQ657 ≥98% 1mg $33 2024-03-01 Buy
Cayman Chemical 19829 LBQ657 ≥98% 5mg $131 2024-03-01 Buy
Cayman Chemical 19829 LBQ657 ≥98% 10mg $245 2024-03-01 Buy
Cayman Chemical 19829 LBQ657 ≥98% 25mg $894 2021-12-16 Buy
Next Last

Properties

Boiling point :705.4±60.0 °C(Predicted)
Density :1?+-.0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMF:30.0(Max Conc. mg/mL);78.24(Max Conc. mM)
DMSO:77.0(Max Conc. mg/mL);200.81(Max Conc. mM)
Ethanol:77.0(Max Conc. mg/mL);200.81(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.3(Max Conc. mM) form :A crystalline solid
pka :4.59±0.23(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Desethyl Sacubitril is an impurity in the synthesis of Sacubitril (S080895), an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.

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Suppliers and manufacturers

Standardpharm Co. Ltd.
BOC Sciences
Career Henan Chemica Co
Hangzhou Huarong Pharm Co., Ltd.
sgtlifesciences pvt ltd
InvivoChem
LEAP CHEM CO., LTD.
China National Standard Pharmaceutical Corporation Limited
Zibo Hangyu Biotechnology Development Co., Ltd
Shanghai Acmec Biochemical Technology Co., Ltd.