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ChemicalBook >> CAS DataBase List >> TP808

TP808

$42 - $1560
Product name: TP808
CAS: 852821-06-8
MF: C26H34N2O5Si
MW: 482.64
EINECS:
MDL Number:MFCD28023585
Synonyms:TP808;(4aS,8aS,9S)-9-(Dimethylamino)-4a-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-8a,9-dihydro-3-(phenylmethoxy)-naphth[2,3-d]isoxazole-4,5(4aH,8H)-dione;(4aS,8aS,9S)-9-(Dimethylamino)-4a-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-8a,9-dihydro-3-(phenylmethoxy)-naphth[2,3-d]isoxazole-4,5(4aH,8H)-dione TP-808;Naphth[2,3-d]isoxazole-4,5(4aH,8H)-dione, 9-(dimethylamino)-4a-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-8a,9-dihydro-3-(phenylmethoxy)-, (4aS,8aS,9S)-;(4aS,8aS,9S)-3-(benzyloxy)-4a-(tert-butyldimethylsilyloxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2,3-d]isoxazole-4,5(4aH,8H)-dione TP808;TP 808, >=98%;3-Benzyloxy-4a-(tert-butyl-dimethyl-silanyloxy)-9-dimethylamino-8a,9-dihydro-4aH,8H-naphtho[2,3-d]isoxazole-4,5-dione;(4aS,8aS,9S)-3-(Benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2

Price44 Properties Safety Information Description

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Brand

aablocks
ACHEMBLOCK
AK Scientific
Ambeed
Arctom
Biorbyt Ltd
Cayman Chemical
Chemenu
Crysdot
DC Chemicals
Matrix Scientific
TRC
Usbiological

Package

5mg
10mg
25mg
50mg
100.00mg
100mg
250.00mg
250mg
1.00g
1G
5G
100 mg
250 mg

Manufactureraablocks
Product numberAA00G51T
Product description(4AS,8aS,9S)-3-(benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2,3-d]isoxazole-4,5(4aH,8H)-dione 97
Packaging25mg
Price$48
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00G51T
Product description(4AS,8aS,9S)-3-(benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2,3-d]isoxazole-4,5(4aH,8H)-dione 97%
Packaging100mg
Price$71
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00G51T
Product description(4AS,8aS,9S)-3-(benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2,3-d]isoxazole-4,5(4aH,8H)-dione 97
Packaging50mg
Price$65
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00G51T
Product description(4AS,8aS,9S)-3-(benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2,3-d]isoxazole-4,5(4aH,8H)-dione 97%
Packaging250mg
Price$125
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product number10398
Product descriptionTP808 98%
Packaging1G
Price$365
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product number10398
Product descriptionTP808 98%
Packaging5G
Price$1560
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number7319CS
Product descriptionCID11363682
Packaging1g
Price$347
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number7319CS
Product descriptionCID11363682
Packaging250mg
Price$176
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number7319CS
Product descriptionCID11363682
Packaging100mg
Price$132
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA140557
Product description(4AS,8aS,9S)-3-(benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2,3-d]isoxazole-4,5(4aH,8H)-dione 97%
Packaging250mg
Price$62
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA140557
Product description(4AS,8aS,9S)-3-(benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2,3-d]isoxazole-4,5(4aH,8H)-dione 97%
Packaging100mg
Price$42
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA140557
Product description(4AS,8aS,9S)-3-(benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2,3-d]isoxazole-4,5(4aH,8H)-dione 97%
Packaging1g
Price$136
Updated2021-12-16
Buy

ManufacturerArctom
Product numberAS007448
Product description(4AS,8aS,9S)-3-(benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2,3-d]isoxazole-4,5(4aH,8H)-dione 97%
Packaging1g
Price$184
Updated2021-12-16
Buy

ManufacturerArctom
Product numberBD-A140557
Product descriptionTP808 97%
Packaging1g
Price$329
Updated2026-05-26
Buy

ManufacturerArctom
Product numberAS007448
Product description(4AS,8aS,9S)-3-(benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2,3-d]isoxazole-4,5(4aH,8H)-dione 97%
Packaging100mg
Price$47
Updated2021-12-16
Buy

ManufacturerArctom
Product numberBD-A140557
Product descriptionTP808 97%
Packaging100mg
Price$73
Updated2026-05-26
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00G51T	(4AS,8aS,9S)-3-(benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2,3-d]isoxazole-4,5(4aH,8H)-dione 97	25mg	$48	2026-05-28	Buy
aablocks	AA00G51T	(4AS,8aS,9S)-3-(benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2,3-d]isoxazole-4,5(4aH,8H)-dione 97%	100mg	$71	2026-05-28	Buy
aablocks	AA00G51T	(4AS,8aS,9S)-3-(benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2,3-d]isoxazole-4,5(4aH,8H)-dione 97	50mg	$65	2026-05-28	Buy
aablocks	AA00G51T	(4AS,8aS,9S)-3-(benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2,3-d]isoxazole-4,5(4aH,8H)-dione 97%	250mg	$125	2026-05-28	Buy
ACHEMBLOCK	10398	TP808 98%	1G	$365	2026-05-27	Buy
ACHEMBLOCK	10398	TP808 98%	5G	$1560	2026-05-27	Buy
AK Scientific	7319CS	CID11363682	1g	$347	2021-12-16	Buy
AK Scientific	7319CS	CID11363682	250mg	$176	2021-12-16	Buy
AK Scientific	7319CS	CID11363682	100mg	$132	2021-12-16	Buy
Ambeed	A140557	(4AS,8aS,9S)-3-(benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2,3-d]isoxazole-4,5(4aH,8H)-dione 97%	250mg	$62	2021-12-16	Buy
Ambeed	A140557	(4AS,8aS,9S)-3-(benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2,3-d]isoxazole-4,5(4aH,8H)-dione 97%	100mg	$42	2021-12-16	Buy
Ambeed	A140557	(4AS,8aS,9S)-3-(benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2,3-d]isoxazole-4,5(4aH,8H)-dione 97%	1g	$136	2021-12-16	Buy
Arctom	AS007448	(4AS,8aS,9S)-3-(benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2,3-d]isoxazole-4,5(4aH,8H)-dione 97%	1g	$184	2021-12-16	Buy
Arctom	BD-A140557	TP808 97%	1g	$329	2026-05-26	Buy
Arctom	AS007448	(4AS,8aS,9S)-3-(benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2,3-d]isoxazole-4,5(4aH,8H)-dione 97%	100mg	$47	2021-12-16	Buy
Arctom	BD-A140557	TP808 97%	100mg	$73	2026-05-26	Buy

Next Last

Properties

Melting point :150-151℃ (ethyl acetate hexane )
Boiling point :573.8±50.0 °C(Predicted)
Density :1.18±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMF: 20 mg/ml
form :A crystalline solid
pka :5.25±0.40(Predicted)
color :White to off-white
optical activity :149.00°(C=0.01g/mL, CHCL3, 20°C, 589nm)
InChIKey :SLXLVVLJLQJWFG-JCWFFFCVSA-N
SMILES :O1C2[C@@H](N(C)C)[C@@]3([H])[C@@](O[Si](C(C)(C)C)(C)C)(C(=O)C=2C(OCC2=CC=CC=C2)=N1)C(=O)C=CC3

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(4aS,8aS,9S)-3-(Benzyloxy)-4a-((tert-butyldimethylsilyl)oxy)-9-(dimethylamino)-8a,9-dihydronaphtho[2,3-d]isoxazole-4,5(4aH,8H)-dione serves as a highlyversatile intermediate for the construction of diverse tetracycline antibiotics.

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Suppliers and manufacturers

Chengdu Sino-Strong Pharmaceutical Co.,Ltd. Suzhou Sino Rare Chemical Co., Ltd. Shanghai Rechem science Co., Ltd. Suzhou Wenzhi Biotechnology Co., Ltd. Tianjin Liontec Biopharma Co.,Ltd. Chengdu Zen Sunda Bio-pharmaceutical Technology Co., Ltd. Jiangsu Aosaikang Pharmaceutical Co., Ltd Shanghai Boyle Chemical Co., Ltd. J & K SCIENTIFIC LTD. JinYan Chemicals(ShangHai) Co.,Ltd.

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TP808

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