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ChemicalBook >> CAS DataBase List >> UNC0646

UNC0646

UNC0646 price.
  • $31 - $3728.1
  • Product name: UNC0646
  • CAS: 1320288-17-2
  • MF: C36H59N7O2
  • MW: 621.9
  • EINECS:
  • MDL Number:MFCD22378486
  • Synonyms:UNC0646;N-(1-cyclohexylpiperidin-4-yl)-2-(4-isopropyl-1,4-diazepan-1-yl)-6-Methoxy-7-(3-(piperidin-1-yl)propoxy)quinazolin-4-aMine;UNC0646/UNC-0646;N-(1-Cyclohexyl-4-piperidinyl)-2-[hexahydro-4-(1-methylethyl)-1H-1,4-diazepin-1-yl]-6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinamine;N-(1-Cyclohexyl-4-piperidinyl)-2-(4-isopropyl-1,4-diazepan-1-yl)- 6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinamine;(1-CYCLOHEXYL-PIPERIDIN-4-YL)-[2-(4-ISOPROPYL-[1,4]DIAZEPAN-1-YL)-6-METHOXY-7-(3-PIPERIDIN-1-YL-PROPOXY)-QUINAZOLIN-4-YL]-AMINE;UNC 0646;UNC0646;UNC-0646;CS-792
Price46 Properties Safety Information Description
46 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 5mg
  • 10mM*1mLinDMSO
  • 10mg
  • 25mg
  • 50
  • 2x25mg
  • 10mM(in1mLDMSO)
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • Manufactureraablocks
  • Product numberAA000ZZN
  • Product descriptionUNC0646 98%
  • Packaging1mg
  • Price$31
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000ZZN
  • Product descriptionUNC0646 98%
  • Packaging5mg
  • Price$42
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000ZZN
  • Product descriptionUNC0646 98%
  • Packaging10mg
  • Price$50
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000ZZN
  • Product descriptionUNC0646 98%
  • Packaging25mg
  • Price$98
  • Updated2026-05-25
  • Buy
  • ManufacturerAK Scientific
  • Product number4143AH
  • Product descriptionN-(1-Cyclohexylpiperidin-4-yl)-2-(4-isopropyl-1,4-diazepan-1-yl)-6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinazolin-4-amine
  • Packaging10mg
  • Price$170
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number4143AH
  • Product descriptionN-(1-Cyclohexylpiperidin-4-yl)-2-(4-isopropyl-1,4-diazepan-1-yl)-6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinazolin-4-amine
  • Packaging50mg
  • Price$612
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA880677
  • Product descriptionUNC0646 98+%
  • Packaging25mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA880677
  • Product descriptionUNC0646 98+%
  • Packaging10mg
  • Price$112
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA880677
  • Product descriptionUNC0646 98+%
  • Packaging5mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4504
  • Product descriptionUNC 0646
  • Packaging10mg
  • Price$142
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4504
  • Product descriptionUNC 0646
  • Packaging50mg
  • Price$432
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4504
  • Product descriptionUNC 0646
  • Packaging5mg
  • Price$101
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4504
  • Product descriptionUNC 0646
  • Packaging10mM(in1mLDMSO)
  • Price$88
  • Updated2026-05-06
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1840
  • Product descriptionUNC0646
  • Packaging25mg
  • Price$401.5
  • Updated2026-05-19
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1840
  • Product descriptionUNC0646 99%
  • Packaging2x25mg
  • Price$638
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1840
  • Product descriptionUNC0646
  • Packaging5mg
  • Price$108.9
  • Updated2026-05-19
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA000ZZN UNC0646 98% 1mg $31 2026-05-25 Buy
aablocks AA000ZZN UNC0646 98% 5mg $42 2026-05-25 Buy
aablocks AA000ZZN UNC0646 98% 10mg $50 2026-05-25 Buy
aablocks AA000ZZN UNC0646 98% 25mg $98 2026-05-25 Buy
AK Scientific 4143AH N-(1-Cyclohexylpiperidin-4-yl)-2-(4-isopropyl-1,4-diazepan-1-yl)-6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinazolin-4-amine 10mg $170 2021-12-16 Buy
AK Scientific 4143AH N-(1-Cyclohexylpiperidin-4-yl)-2-(4-isopropyl-1,4-diazepan-1-yl)-6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinazolin-4-amine 50mg $612 2021-12-16 Buy
Ambeed A880677 UNC0646 98+% 25mg $190 2021-12-16 Buy
Ambeed A880677 UNC0646 98+% 10mg $112 2021-12-16 Buy
Ambeed A880677 UNC0646 98+% 5mg $66 2021-12-16 Buy
ApexBio Technology A4504 UNC 0646 10mg $142 2026-05-06 Buy
ApexBio Technology A4504 UNC 0646 50mg $432 2026-05-06 Buy
ApexBio Technology A4504 UNC 0646 5mg $101 2026-05-06 Buy
ApexBio Technology A4504 UNC 0646 10mM(in1mLDMSO) $88 2026-05-06 Buy
Axon Medchem Axon1840 UNC0646 25mg $401.5 2026-05-19 Buy
Axon Medchem Axon1840 UNC0646 99% 2x25mg $638 2021-12-16 Buy
Axon Medchem Axon1840 UNC0646 5mg $108.9 2026-05-19 Buy
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Properties

Boiling point :754.6±70.0 °C(Predicted)
Density :1.128±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: soluble2mg/mL, clear (warmed)
pka :9.34±0.70(Predicted)
form :powder
color :white to beige
InChIKey :OUKWLRHRXOPODD-UHFFFAOYSA-N
SMILES :N2(CCC(CC2)Nc3nc(nc5c3cc(c(c5)OCCCN6CCCCC6)OC)N4CCN(CCC4)C(C)C)C1CCCCC1

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

G9a and G9a-like protein (GLP) are euchromatic histone-lysine methyltransferases (EHMT2 and EHMT1, respectively) that can heterodimerize with each other to methylate several proteins in addition to histone H3. UNC0646 is a potent and selective inhibitor of G9a and GLP activities in vitro (IC50s = 6 and 15 nM, respectively) and G9a/GLP-mediated dimethylation of histone 3 on lysine 9 in MDA-MB-231 cells (IC50 = 26 nM). It is highly selective for G9a/GLP over several other protein lysine and arginine methyltransferases. UNC0646 potently inhibits G9a/GLP activity in a variety of cancer cell lines as well as in the human fetal lung IMR-90 line. This compound selectively targets the corepressor function of G9a without affecting its ability to act as a coactivator with glucocorticoid receptor.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
UNC0646
$58.00
UNC0646 CAS:1320288-17-2
Career Henan Chemica Co
HANGZHOU LEAP CHEM CO., LTD.
Aladdin Scientific
NANJING YINGWEN BIOTECHNOLOGY CO LTD
Amadis Chemical Company Limited Chembest Research Laboratories Limited Bide Pharmatech Ltd. Shanghai Lollane Biological Technology Co.,Ltd. YouCoChem (Beijing) Chemical Technology Co., Ltd.