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ChemicalBook >> CAS DataBase List >> Verteporfin

Verteporfin

Verteporfin price.
  • $24 - $2900
  • Product name: Verteporfin
  • CAS: 129497-78-5
  • MF: 2C41H42N4O8
  • MW: 1437.61
  • EINECS:
  • MDL Number:MFCD11982858
  • Synonyms:Verteporfin(DB00460);Verteprofin;Verteporfin;Verteporphin;24H,26H-Benzo[b]porphine-9,13-dipropanoic acid, 18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-, monomethyl ester, (4R,4aS)-rel-;VERTEPIRFIN;9-methyl (I)13-methyl (II)trans-(±)- 18-ethenyl- 4,4a-dihydro-3,4 -bis(methoxycarbonyl)- 4a,8,14,19-tetramethyl- 23H,25H-benzo[b]porphine- 9,13- dipropanoate;(4R,4aS)-rel-18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoic acid monomethyl ester
44 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 1unit
  • 5mg
  • 2x5mg
  • 10mg
  • 25mg
  • 50mg
  • 200mg
  • 250mg
  • 10mM(in 1mL DMSO)
  • 100mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberK343
  • Product descriptionVerteporfin
  • Packaging100mg
  • Price$1331
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA138297
  • Product description(4R,4aS)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoicacidmonomethylester 98+%
  • Packaging1mg
  • Price$24
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA138297
  • Product description(4R,4aS)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoicacidmonomethylester 98+%
  • Packaging5mg
  • Price$79
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA138297
  • Product description(4R,4aS)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoicacidmonomethylester 98+%
  • Packaging10mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA138297
  • Product description(4R,4aS)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoicacidmonomethylester 98+%
  • Packaging25mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA138297
  • Product description(4R,4aS)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoicacidmonomethylester 98+%
  • Packaging50mg
  • Price$427
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA138297
  • Product description(4R,4aS)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoicacidmonomethylester 98+%
  • Packaging100mg
  • Price$623
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0026023
  • Product descriptionVERTEPORFIN 95.00%
  • Packaging5MG
  • Price$499.51
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8327
  • Product descriptionVerteporfin
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8327
  • Product descriptionVerteporfin
  • Packaging5mg
  • Price$104
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8327
  • Product descriptionVerteporfin
  • Packaging10mM(in 1mL DMSO)
  • Price$156
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8327
  • Product descriptionVerteporfin
  • Packaging25mg
  • Price$285
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS448254
  • Product description(4R,4aS)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoicacidmonomethylester ≥98%
  • Packaging1mg
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS448254
  • Product description(4R,4aS)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoicacidmonomethylester ≥98%
  • Packaging5mg
  • Price$78
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS448254
  • Product description(4R,4aS)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoicacidmonomethylester ≥98%
  • Packaging10mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS448254
  • Product description(4R,4aS)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoicacidmonomethylester ≥98%
  • Packaging25mg
  • Price$238
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific K343 Verteporfin 100mg $1331 2021-12-16 Buy
Ambeed A138297 (4R,4aS)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoicacidmonomethylester 98+% 1mg $24 2021-12-16 Buy
Ambeed A138297 (4R,4aS)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoicacidmonomethylester 98+% 5mg $79 2021-12-16 Buy
Ambeed A138297 (4R,4aS)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoicacidmonomethylester 98+% 10mg $120 2021-12-16 Buy
Ambeed A138297 (4R,4aS)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoicacidmonomethylester 98+% 25mg $240 2021-12-16 Buy
Ambeed A138297 (4R,4aS)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoicacidmonomethylester 98+% 50mg $427 2021-12-16 Buy
Ambeed A138297 (4R,4aS)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoicacidmonomethylester 98+% 100mg $623 2021-12-16 Buy
American Custom Chemicals Corporation API0026023 VERTEPORFIN 95.00% 5MG $499.51 2021-12-16 Buy
ApexBio Technology A8327 Verteporfin 1unit $28 2021-12-16 Buy
ApexBio Technology A8327 Verteporfin 5mg $104 2021-12-16 Buy
ApexBio Technology A8327 Verteporfin 10mM(in 1mL DMSO) $156 2021-12-16 Buy
ApexBio Technology A8327 Verteporfin 25mg $285 2021-12-16 Buy
Arctom AS448254 (4R,4aS)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoicacidmonomethylester ≥98% 1mg $35 2021-12-16 Buy
Arctom AS448254 (4R,4aS)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoicacidmonomethylester ≥98% 5mg $78 2021-12-16 Buy
Arctom AS448254 (4R,4aS)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoicacidmonomethylester ≥98% 10mg $119 2021-12-16 Buy
Arctom AS448254 (4R,4aS)-rel-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-Benzo[b]porphine-9,13-dipropanoicacidmonomethylester ≥98% 25mg $238 2021-12-16 Buy

Properties

storage temp. :-20°C
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :powder
color :Black
Stability :Stable for 2 years from date of purchsae as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :YHNBVDZVUQFVLS-RDSGBMLISA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Verteporfin is a photosensitizer used during photodynamic therapy to eliminate abnormal blood vessels in the eye that are associated with conditions such as macular degeneration. It accumulates in these abnormal blood vessels and, when activated by nonthermal red light with a wavelength of 693 nm in the presence of oxygen, produces a highly reactive short-lived singlet oxygen and other reactive oxygen radicals, generating local damage to the endothelium and vessel occlusion. Verteporfin can also inhibit autophagosome formation by directly targeting and modifying p62, a scaffold and adaptor protein that binds both polyubiquitinated proteins destined for degradation and LC3 on autophagosomal membranes.

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