4,6-亚乙基-alpha-D-葡萄糖
中文名称 | 4,6-亚乙基-alpha-D-葡萄糖 |
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中文同义词 | 4,6-亚乙基-Α-D-葡萄糖;4,6-O-亚乙基-Α-D-吡喃葡萄糖;4,6-O-亚乙基-Α4,6-O-亚乙基-Α-D-吡喃葡糖;4,6-O-亚乙基-Α-D-葡糖;4,6-O-亚乙基-Α-D-葡萄糖;4,6-亚乙基-alpha-D-葡萄糖;4 6 0-乙缩醛-D-葡萄糖 |
英文名称 | 4,6-O-Ethylidene-alpha-D-glucose |
英文同义词 | (2R,3R)-2,3-dihydroxy-3-((4R,5R)-5-hydroxy-2-methyl-1,3-dioxan-4-yl)propanal;(4aR,6S,7R,8R,8aS)-2-Methylhexahydropyrano[3,2-d][1,3]dioxine-6,7,8-triol;(4AR,7R,8R,8aS)-2-Methylhexahydropyrano-[3,2-d][1,3]dioxine-6,7,8-triol;NSC 89726;-D-glucopyranose;4,6-O-Ethylidene-α4,6-O-ETHYLIDENE-A-D-GLUCOSE;4,6-O-ETHYLIDENE-ALPHA-D-GLUCOPYRANOSE |
CAS号 | 13224-99-2 |
分子式 | C8H14O6 |
分子量 | 206.19 |
EINECS号 | 236-198-2 |
相关类别 | 单糖;Carbohydrate Synthesis;Specialty Synthesis;Monosaccharides;Sugars;Sugars, Carbohydrates & Glucosides;Biochemistry;Glucose;O-Substituted Sugars |
Mol文件 | 13224-99-2.mol |
结构式 |
4,6-亚乙基-alpha-D-葡萄糖 性质
熔点 | 168-170 °C(lit.) |
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沸点 | 386.6±42.0 °C(Predicted) |
密度 | 1.446±0.06 g/cm3(Predicted) |
闪点 | >110°(230°F) |
溶解度 | 乙醇、水 |
酸度系数(pKa) | 12.01±0.70(Predicted) |
形态 | 粉末 |
颜色 | 白色至类白色 |
水溶解性 | almost transparency |
LogP | 0.54 |
CAS 数据库 | 13224-99-2(CAS DataBase Reference) |
GLUT1
|
Human Endogenous Metabolite
|
4,6-O-ethylidene-α-D-glucose (Ethylidene-glucose) shows poor affinity for malarial hexose transporter (PfHT1; K
i
>50 mM). 4,6-O-ethylidene-α-D-glucose inhibits wild-type transport with a K
i
of approximately 12 mM, but this is increased to greater than 120 mM in the Gln282-Leu mutant.
4,6-O-ethylidene-α-D-glucose inhibits glucose exit competitively but its penetration into human red cells is unaffected by glucose in the medium. The potentiation of the development of FDNB inhibition by sugars in the incubating medium is absent when 4,6-O-ethylidene-α-D-glucose is used and there is a slight protective action. 4,6-O-ethylidene-α-D-glucose penetrates human red cells by simple diffusion supported by its penetration of guinea-pig red cells at similar rates, by the occurrence of osmotic haemolysis in isosmotic solutions which is unaffected by copper ions and by the relatively high ether/water partition of the compound.
安全信息
安全说明 | 24/25 |
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WGK Germany | 3 |
海关编码 | 29400090 |
提供商 | 语言 |
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英文
|
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/08/19 | HY-N7433 | 4,6-亚乙基-alpha-D-葡萄糖 4,6-O-Ethylidene-α-D-glucose | 13224-99-2 | 50mg | 1000元 |
2024/08/19 | HY-N7433 | 4,6-亚乙基-alpha-D-葡萄糖 4,6-O-Ethylidene-α-D-glucose | 13224-99-2 | 10mM * 1mLin DMSO | 1100元 |