ChemicalBook CAS DataBase List 1,2-BIS-(4-FLUOROPHENYL)ETHANONE

1,2-BIS-(4-FLUOROPHENYL)ETHANONE synthesis

13synthesis methods

Product Name:1,2-BIS-(4-FLUOROPHENYL)ETHANONE
CAS Number:366-68-7
Molecular formula:C14H10F2O
Molecular Weight:232.23

459-56-3 Synthesis

459-56-3
299 suppliers
$6.00/5g

366-68-7
31 suppliers
$60.00/100 mg

Yield: 74.3%

Reaction Conditions:

with Zn_0.6In₂S_3.6 in acetonitrile at 20; for 15 h;Inert atmosphere;Sealed tube;Irradiation;

Steps:

7 Example 7
In a 5 ml quartz glass reaction tube, 0.2 mmol of 4-fluorobenzyl alcohol was added, and 20 mg of Zn0.6In2S3.6 was weighed to catalyze the reaction, and 1.0 ml of acetonitrile was added thereto, The reaction tube was replaced with argon gas and sealed, and the ambient temperature 6W LED was illuminated for 15 hours. After completion of the reaction, the product was chromatographed, and the mass spectrum showed a molecular weight consistent with 4,4'-difluorodiphenylethanone, and the yield was 74.3%.

References:

Dalian Institute of Chemical Physics;Wang Feng;Luo Nengchao;Wang Min;Hou Tingting;Chi Rihan;Li Hongji;Liu Huifang CN108440259, 2018, A Location in patent:Paragraph 0039; 0040

579-39-5 Synthesis