1-[(2-METHOXYPHENYL)CARBONYL]PIPERAZINE synthesis

5synthesis methods

Product Name:1-[(2-METHOXYPHENYL)CARBONYL]PIPERAZINE
CAS Number:100939-88-6
Molecular formula:C12H16N2O2
Molecular Weight:220.27

1-Piperazinecarboxylic acid, 4-(2-methoxybenzoyl)-, 1,1-dimethylethyl ester

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Yield:100939-88-6 100%

Reaction Conditions:

with trifluoroacetic acid

Steps:

Intermediate Product 17: (2-Methoxy-phenyl)-piperazin-1-yl-methanone

Intermediate Product 17: (2-Methoxy-phenyl)-piperazin-1-yl-methanone The preparation was carried out analogously to intermediate product 16 according to process step 5 using 4-(2-methoxy-benzoyl)-piperazine-1-carboxylic acid tert-butyl ester (intermediate product 15) (1.58 g, 4.95 mmol) and TFA (20% in MC, 7 ml) to give intermediate product 17 (1.09 g, 100%).

References:

US2012/214798,2012,A1

110-85-0 Synthesis