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179534-78-2

1-[2-(TRIFLUOROMETHYL)BENZOYL]PIPERAZINE synthesis

3synthesis methods
4-(2-(Trifluoromethyl)benzoyl)piperazine-1-carboxylic acid tert-butyl ester

840491-84-1
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1-[2-(TRIFLUOROMETHYL)BENZOYL]PIPERAZINE

179534-78-2
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Yield:179534-78-2 93%

Reaction Conditions:

with trifluoroacetic acid in dichloromethane at 20;

References:

Li, Chun Sing;Belair, Liette;Guay, Jocelyne;Murgasva, Renata;Sturkenboom, Wayne;Ramtohul, Yeeman K.;Zhang, Lei;Huang, Zheng [Bioorganic and Medicinal Chemistry Letters,2009,vol. 19,# 17,p. 5214 - 5217] Location in patent:scheme or table