1-(3-methoxybenzyl)piperazine dihydrochloride synthesis

1synthesis methods

110-85-0 Synthesis

Yield:113698-79-6 35%

Reaction Conditions:

with sodium hydroxide in formic acid;1.) 100 deg C, 5 h; 2.) reflux, 2 h;

References:

Ohtaka;Fujimoto;Yoshida;Kanazawa;Ito;Tsukamoto [Chemical and Pharmaceutical Bulletin,1987,vol. 35,# 7,p. 2782 - 2791]

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