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1-(4-BROMOPHENYL)-5-CHLORO-1-OXOPENTANE synthesis

2synthesis methods
-

Yield:54874-12-3 81%

Reaction Conditions:

with 1,10-Phenanthroline;tert-butylhypochlorite;silver trifluoromethanesulfonate in acetonitrile at 20; for 48 h;Inert atmosphere;Schlenk technique;regioselective reaction;

References:

Huang, Feng-Qing;Xie, Jian;Sun, Jian-Guo;Wang, Yue-Wei;Dong, Xin;Qi, Lian-Wen;Zhang, Bo [Organic Letters,2016,vol. 18,# 4,p. 684 - 687] Location in patent:supporting information