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Bromobenzene

Bromobenzene
Bromobenzene structure
CAS No.
108-86-1
Chemical Name:
Bromobenzene
Synonyms
Brombenzol;NCI-C55492;Bromobenzol;BROMOBENZENE;bromo-benzen;Benzene,bromo-;1-Bromobenzene;PHENYL BROMIDE;Bromobenzene 1;3-Bromobenzene
CBNumber:
CB6235569
Molecular Formula:
C6H5Br
Formula Weight:
157.01
MOL File:
108-86-1.mol

Bromobenzene Properties

Melting point:
-31 °C
Boiling point:
156 °C(lit.)
Density 
1.491 g/mL at 25 °C(lit.)
vapor density 
5.41 (vs air)
vapor pressure 
10 mm Hg ( 40 °C)
refractive index 
n20/D 1.559(lit.)
Flash point:
124 °F
storage temp. 
2-8°C
solubility 
Miscible with diethyl ether, alcohol, carbon tetrachloride, chloroform and benzene.
form 
Liquid
color 
Clear colorless to faintly yellow
Odor
Pleasant.
explosive limit
0.5-2.5%(V)
Water Solubility 
insoluble. <0.1 g/100 mL at 20.5 ºC
Merck 
14,1406
BRN 
1236661
Henry's Law Constant
2.47 at 25 °C (gas stripping-GC, Shiu and Mackay, 1997)
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey
QARVLSVVCXYDNA-UHFFFAOYSA-N
CAS DataBase Reference
108-86-1(CAS DataBase Reference)
EWG's Food Scores
2
FDA UNII
CO4D5J547L
NIST Chemistry Reference
Benzene, bromo-(108-86-1)
EPA Substance Registry System
Bromobenzene (108-86-1)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS02,GHS07,GHS09,GHS06,GHS08
Signal word  Danger
Hazard statements  H319-H373-H303-H226-H315-H411-H301-H311-H331-H370
Precautionary statements  P210-P233-P240-P241+P242+P243-P264-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P314-P391-P403+P235-P501-P273-P260-P280-P301+P310-P311-P241-P280a-P303+P361+P353-P501a
Hazard Codes  Xi,N,F,T
Risk Statements  10-38-51/53-39/23/24/25-23/24/25
Safety Statements  61-45-36/37
RIDADR  UN 2514 3/PG 3
WGK Germany  2
RTECS  CY9000000
Autoignition Temperature 565 °C
TSCA  Yes
HS Code  2903 99 80
HazardClass  3
PackingGroup  III
Toxicity LD50 orally in Rabbit: 2383 mg/kg
NFPA 704
2
1 0

Bromobenzene price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 16350 Bromobenzene ≥99.5% (GC) 108-86-1 100ml $32.4 2020-08-18 Buy
Sigma-Aldrich 16350 Bromobenzene ≥99.5% (GC) 108-86-1 1l $154 2020-08-18 Buy
TCI Chemical B0439 Bromobenzene >99.0%(GC) 108-86-1 25g $15 2020-06-24 Buy
TCI Chemical B0439 Bromobenzene >99.0%(GC) 108-86-1 500g $27 2020-06-24 Buy
Alfa Aesar A11407 Bromobenzene, 99% 108-86-1 500g $34.5 2020-06-24 Buy

Bromobenzene Chemical Properties,Uses,Production

Chemical Properties

colourless liquid

Physical properties

Mobile, clear, colorless to pale yellow liquid with an aromatic odor. The reported odor threshold is 4.6 ppm (Mateson, 1955).

Uses

The compound is employed as a starting material in organic syntheses in which a Grignard intermediate (phenyl magnesium bromide) is used. The material is a chemical precursor for certain agricultural products and has been used as an additive to motor oils. Bromobenzene has also been used as a high-density solvent for chemical recrystallization processes.

Uses

In organic synthesis, especially to make phenyl magnesium bromide; as solvent, especially for crystallizations on a large scale and where a heavy liquid is desirable; as additive to motor oils.

Synthesis Reference(s)

The Journal of Organic Chemistry, 30, p. 304, 1965 DOI: 10.1021/jo01012a512
Tetrahedron Letters, 26, p. 1935, 1985

General Description

Mobile clear colorless liquid with a pungent odor. Flash point 124°F. Denser than water and insoluble in water. Hence sinks in water. Vapors are heavier than air. A skin irritant.

Air & Water Reactions

Flammable. Insoluble in water.

Reactivity Profile

Bromobenzene may be sensitive to light. May react with oxidizing agents .

Hazard

Skin irritant. Moderate fire risk.

Health Hazard

Contact with liquid causes irritation of eyes and mild irritation of skin. Ingestion causes mild irritation of mouth and stomach.

Health Hazard

The acute toxicity of bromobenzene is lowin test animals. The toxic symptoms includesomnolence, respiratory stimulation, and muscle contraction. The oral LD50 value in rats is2700 mg/kg.

Fire Hazard

Special Hazards of Combustion Products: Irritating hydrogen bromide and other gases may be produced in fire.

Chemical Reactivity

Reactivity with Water No reaction; Reactivity with Common Materials: No reactions; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Safety Profile

Moderately toxic by ingestion, subcutaneous, and intraperitoneal routes. LWdly toxic by inhalation. An eye and mucous membrane irritant. Mutation data reported. Flammable liquid when exposed to heat, sparks, or flame. Can react with oxidtzing materials. To fight fire, use water to blanket fire, foam, CO2, water spray or mist, dry chemical. Violent reaction with bromobutane + sodium when heated above 30℃. When heated to decomposition it emits toxic fumes of Br-. See also BROMIDES.

Source

No MCLs, MCLGs, or DWELs have been proposed (U.S. EPA, 2000).
Storm water runoff, waste motor oils, improper disposal of laboratory solvent containing bromobenzene (quoted, Verschueren, 1983)

Environmental Fate

Biological. In activated sludge, 34.8% of the applied bromobenzene mineralized to carbon dioxide after 5 d (Freitag et al., 1985).
Photolytic. A carbon dioxide yield of 19.7% was achieved when bromobenzene adsorbed on silica gel was irradiated with light (λ >290 nm) for 17 h (Freitag et al., 1985). Irradiation of bromobenzene in air containing nitrogen oxides gave phenol, 4-nitrophenol, 2,4-dinitrophenol, 4- bromophenol, 3-bromonitrobenzene, 3-bromo-2-nitrophenol, 3-bromo-4-nitrophenol, 3-bromo-6-nitrophenol, 2-bromo-4-nitrophenol, and 2,6-dibromo-4-nitrophenol (Nojima et al., 1980).
Chemical/Physical. Bromobenzene will not hydrolyze to any reasonable extent. In the laboratory, no change in concentration was observed after 29 d at 85 °C in 0.1M NaOH and 0.1M HCl (Kollig, 1995).
Augusti et al. (1998) conducted kinetic studies for the reaction of bromobenzene (0.2 mM) and other monocyclic aromatics with Fenton’s reagent (8 mM hydrogen peroxide; [Fe+2] = 0.1 mM) at 25 °C. They reported a reaction rate constant of 0.0740/min.

Metabolic pathway

Bromobenzene and chlorobenzene are metabolized by human and mouse hepatic microsomes to two different epoxide intermediates, which rearrange to form either o- or p-bromo- and o- or p-chlorophenols, respectively. Humans preferentially metabolize halobenzenes through the hepatotoxic 3,4-epoxide pathway, suggesting that humans may be more susceptible than mice to halobenzene-induced hepatotoxicity.

Purification Methods

Wash bromobenzene vigorously with conc H2SO4, then 10% NaOH or NaHCO3 solutions, and H2O. Dry it with CaCl2 or Na2SO4, or pass it through activated alumina, before refluxing with, and distilling from, CaH2, using a glass helix-packed column. [Beilstein 5 IV 670.]

Bromobenzene Preparation Products And Raw materials

Raw materials

Preparation Products


Bromobenzene Suppliers

Global( 364)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21842 58
Yancheng Longshen Chemical Co.,Ltd.
86-0515-88706880 86-18352073353
86-0515-88706880 sales@longshenchem.com CHINA 78 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22624 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 2754 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30039 58
NINGBO INNO PHARMCHEM CO., LTD.
13867897135
sales@nbinno.com CHINA 925 58
Hebei Huanhao Biotechnology Co., Ltd.
+8618034552304
86-0311-83975816 cathylee@hbhuanhao.com CHINA 837 58
Zhejiang ZETian Fine Chemicals Co. LTD
+86-18957127338
QQ:800182836 stella@zetchem.com CHINA 2886 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28231 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 10126 58

View Lastest Price from Bromobenzene manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2020-08-13 Bromobenzene
108-86-1
US $150.00 / ASSAYS 10g 99.5% 10 MT Hebei Huanhao Biotechnology Co., Ltd.
2020-08-19 Bromobenzene
108-86-1
US $15.00-10.00 / KG 1KG 99.8% 10tons Hebei Runbin Biotechnology Co. LTD
2020-07-08 Bromobenzene
108-86-1
US $1.00 / KG 1KG >99% 10000 Kilogram/Kilograms per Month Hebei Xibaijie Biotechnology Co., Ltd.

Bromobenzene Spectrum


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