1,4-Dibromobenzene synthesis
- Product Name:1,4-Dibromobenzene
- CAS Number:106-37-6
- Molecular formula:C6H4Br2
- Molecular Weight:235.9
374564-35-9
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$7.00/250mg
106-37-6
470 suppliers
$9.00/5g
Yield:106-37-6 99%
Reaction Conditions:
with pyridinium hydrobromide perbromide in tetrahydrofuran;water at 20; for 0.333333 h;chemoselective reaction;
Steps:
4.2. Typical procedure for bromodeboronation reactions
General procedure: The trifluoroborate (1.0 mmol) was dissolved in (1:1 v/v) mixture of tetrahydrofuran and water (10 mL). Pyridinium tribromide (or tetrabutylammonium tribromide) (1.0 mmol) was added to this solution. The mixture was stirred for the appropriate time and temperature (Tables 1and 2) and then diluted with 10 mL of ether. The aqueous layer was extracted twice with ether (5 mL) and the combined organic phase was dried over anhydrous Na2SO4. After evaporation of the solvent the residue was purified by silica gel column chromatography [elute: hexane (or pentane)-ethyl acetate (or Et2O)].
References:
Yao, Min-Liang;Kabalka, George W.;Blevins, David W.;Reddy, Marepally Srinivasa;Yong, Li [Tetrahedron,2012,vol. 68,# 19,p. 3738 - 3743] Location in patent:experimental part
106-40-1
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$12.00/5g
106-37-6
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$9.00/5g
5467-74-3
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$8.00/1g
106-37-6
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$9.00/5g
673-40-5
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$52.00/5g
106-37-6
470 suppliers
$9.00/5g
108-86-1
492 suppliers
$10.00/5g
106-37-6
470 suppliers
$9.00/5g