ChemicalBook CAS DataBase List 1-Acetamido-7-hydroxynaphthalene

1-Acetamido-7-hydroxynaphthalene synthesis

6synthesis methods

Product Name:1-Acetamido-7-hydroxynaphthalene
CAS Number:6470-18-4
Molecular formula:C12H11NO2
Molecular Weight:201.22

118-46-7 Synthesis

118-46-7
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64-19-7 Synthesis

64-19-7
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6470-18-4
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$78.00/10g

Yield:6470-18-4 120 g

Reaction Conditions:

with sodium hydroxide at 20 - 40; for 2 h;

Steps:

Dissolve 0.5 mole of 8-amino-2-naphthol in a 400-milliliter sodium hydroxide solution and control the temperature at 20-40°C.0.76 moles of glacial acetic acid are slowly added dropwise and the reaction is maintained at this temperature for 2 hours.After the reaction was completed, 60 g of soda ash was added to adjust the pH to 8.5 to 9.0, and the temperature was raised to 60 to 95° C., held for 15 minutes, cooled to 20° C. or less, and stirred for 1 hour. With suction filtration, pressure drying, and the filtrate is used as a backup, the filter cake is dried at 80-90° C., and the dried product is 100% refined and 120 g, the content is ≥90% (coupling value), and the purity of 8-acetamido-2-naphthol is 99%.The organic solvent used in the present invention can be recycled after being filtered out for a long period of time without any waste water being produced.

References:

CN107915652,2018,A Location in patent:Paragraph 0025; 0026

118-46-7 Synthesis

118-46-7
208 suppliers
$10.00/1g