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1-BOC-4-ETHYL-4-FORMYL-PIPERIDINE synthesis

3synthesis methods
124443-68-1 Synthesis
N-Boc-Piperidine-4-carboxylic acid methyl ester

124443-68-1
267 suppliers
$6.00/5g

1-BOC-4-ETHYL-4-FORMYL-PIPERIDINE

885523-41-1
5 suppliers
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: LDA / tetrahydrofuran / -78 °C
2: LAH / tetrahydrofuran / 20 °C
3: SO3*Py; NEt3 / dimethylsulfoxide / 20 °C

References:

Ogino, Yoshio;Ohtake, Norikazu;Kobayashi, Kensuke;Kimura, Toshifumi;Fujikawa, Toru;Hasegawa, Takuro;Noguchi, Kazuhito;Mase, Toshiaki [Bioorganic and Medicinal Chemistry Letters,2003,vol. 13,# 13,p. 2167 - 2172]