1-(boc-aMino)-(pyrrolidin-3-yl)-cyclopropane synthesis
- Product Name:1-(boc-aMino)-(pyrrolidin-3-yl)-cyclopropane
- CAS Number:185693-07-6
- Molecular formula:C12H22N2O2
- Molecular Weight:226.32
24424-99-5
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185693-07-6
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Yield:-
Steps:
Multi-step reaction with 2 steps
1: sodium hydrogencarbonate / tetrahydrofuran; water / 2 h / 25 °C
2: hydrogen; palladium 10% on activated carbon / methanol / 2 h / 50 °C / 2585.81 Torr
References:
NOVARTIS AG;FIDALGO, Javier De Vicente;HE, Haiying;HU, Cheng;JIANG, Zhigan;LI, Xiaolin;LU, Peichao;MERGO, Wosenu;MUTNICK, Daniel;RECK, Folkert;RIVKIN, Alexey;SKEPPER, Colin Kevin;WANG, Xiaojing Michael;XIA, Jianhua;XU, Yongjin WO2016/20836, 2016, A1