ChemicalBook CAS DataBase List 1-BROMO-8-PHENYLOCTANE

1-BROMO-8-PHENYLOCTANE synthesis

12synthesis methods

Product Name:1-BROMO-8-PHENYLOCTANE
CAS Number:54646-75-2
Molecular formula:C14H21Br
Molecular Weight:269.22

111-87-5 Synthesis

111-87-5
700 suppliers
$6.00/100g

558-13-4 Synthesis

558-13-4
251 suppliers
$10.00/1g

54646-75-2
62 suppliers
$45.00/50mg

Yield:-

Reaction Conditions:

with triphenylphosphine in dichloromethane

Steps:

1.a (a)
To an ice cold solution of the octanol (ca. 19.8 mmoles) and carbon tetrabromide (21.98 mmoles) in methylene chloride (50 ml) was added triphenylphosphine (22.30 mmoles) in methylene chloride (50 ml) and the resulting solution was stirred for 2.5 hours. The volatiles were evaporated and the residue was taken up in ether (100 ml), cooled in ice, and filtered. The filtrate was evaporated and distilled to afford 8-phenyloctyl bromide as an oil.

References:

SmithKline Beecham Corporation US4954513, 1990, A

10472-97-6 Synthesis