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1-METHYL-4,5,6,7-TETRAHYDRO-1H-BENZIMIDAZOLE synthesis

4synthesis methods
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Yield:1837-49-6 63%

Reaction Conditions:

Stage #1: 4,5,6,7-tetrahydro-1H-benzimidazolewith sodium hydride in N,N-dimethyl-formamide at 20; for 1.5 h;
Stage #2: methyl iodide in N,N-dimethyl-formamide at 20;

References:

Lovely, Carl J.;Du, Hongwang;He, Yong;Dias, H.V. Rasika [Organic Letters,2004,vol. 6,# 5,p. 735 - 738]