1-(Phenylsulfonyl)piperidine, 97% synthesis
- Product Name:1-(Phenylsulfonyl)piperidine, 97%
- CAS Number:5033-23-8
- Molecular formula:C11H15NO2S
- Molecular Weight:225.31
Yield:5033-23-8 97%
Reaction Conditions:
with Fe3O4-supported (diisopropylamino)acetamide in dichloromethane at 25;
Steps:
General procedure: A mixture of the reactant and Fe3O4-DIPA in CH2Cl2 (1 ml) was shaken at 25 oC using a VXR-S-1 vortexer. Upon completion of reaction as indicated by the absence of the limiting agent in TLC, Fe3O4-DIPA was separated by magnetic separation using a magnetightTM separation stand, followed by successive washing of the support with CH2Cl2. The combined solution was concentrated before treating with Si-DCT. 1H NMR spectra for all the synthesized compounds were consistent with those in the reported literature.
References:
Rattanaburi, Parintip;Khumraksa, Bannarak;Pattarawarapan, Mookda [Tetrahedron Letters,2012,vol. 53,# 22,p. 2689 - 2693] Location in patent:supporting information; experimental part
