1-(6-bromopyridin-3-yl)-N,N-dimethylpiperidin-4-amine synthesis
- Product Name:1-(6-bromopyridin-3-yl)-N,N-dimethylpiperidin-4-amine
- CAS Number:1169698-77-4
- Molecular formula:C12H18BrN3
- Molecular Weight:284.2
73290-22-9
340 suppliers
$6.00/1g
50533-97-6
188 suppliers
$11.00/1g
1169698-77-4
19 suppliers
$975.00/1g
Yield:1169698-77-4 55%
Reaction Conditions:
with tris-(dibenzylideneacetone)dipalladium(0);4,5-bis(diphenylphosphino)-9,9-dimethylxanthene;sodium t-butanolate in toluene at 100; for 6 h;Inert atmosphere;
References:
Rye, Carl S.;Chessum, Nicola E. A.;Lamont, Scott;Pike, Kurt G.;Faulder, Paul;Demeritt, Julie;Kemmitt, Paul;Tucker, Julie;Zani, Lorenzo;Cheeseman, Matthew D.;Isaac, Rosie;Goodwin, Louise;Boros, Joanna;Raynaud, Florence;Hayes, Angela;Henley, Alan T.;De Billy, Emmanuel;Lynch, Christopher J.;Sharp, Swee Y.;Te Poele, Robert;Fee, Lisa O';Foote, Kevin M.;Green, Stephen;Workman, Paul;Jones, Keith [MedChemComm,2016,vol. 7,# 8,p. 1580 - 1586] Location in patent:supporting information