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1173160-51-4

6H-Purin-6-one, 2-amino-9-α-L-arabinofuranosyl-1,9-dihydro- synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: N,N-dimethyl acetamide / 150 °C
2.1: trimethylsilyl trifluoromethanesulfonate / 1,2-dichloro-ethane / 6 h / 60 °C
2.2: 6 h / 40 - 42 °C / Enzymatic reaction
3.1: ammonia / methanol / 10 h / 25 - 28 °C

References:

Singh, Sunil K.;Sharma, Vivek K.;Olsen, Carl E.;Wengel, Jesper;Parmar, Virinder S.;Prasad, Ashok K. [Journal of Organic Chemistry,2010,vol. 75,# 22,p. 7932 - 7935]