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18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
ChemicalBook CAS DataBase List tert-butyl (3S,4S)-3-fluoro-4-hydroxypiperidine-1-carboxylate

tert-butyl (3S,4S)-3-fluoro-4-hydroxypiperidine-1-carboxylate synthesis

3synthesis methods
211108-50-8 Synthesis
TERT-BUTYL 3-FLUORO-4-OXOPIPERIDINE-1-CARBOXYLATE

211108-50-8
183 suppliers
$8.00/250mg

tert-butyl (3S,4S)-3-fluoro-4-hydroxypiperidine-1-carboxylate

1174020-44-0
61 suppliers
$180.00/250mg

trans-tert-butyl 3-fluoro-4-hydroxypiperidine-1-carboxylate

1174020-43-9
52 suppliers
$495.00/1G

-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: methanol; sodium tetrahydroborate / 2 h
2: Chiralpak AD-H / methanol / Resolution of racemate

References:

PFIZER INC.;DAROUT, Etzer;GUIMARAES, Cristiano;MASCITTI, Vincent;MCCLURE, Kim F. WO2013/11402, 2013, A1

79099-07-3 Synthesis
N-(tert-Butoxycarbonyl)-4-piperidone

79099-07-3
557 suppliers
$5.00/5g

tert-butyl (3S,4S)-3-fluoro-4-hydroxypiperidine-1-carboxylate

1174020-44-0
61 suppliers
$180.00/250mg

trans-tert-butyl 3-fluoro-4-hydroxypiperidine-1-carboxylate

1174020-43-9
52 suppliers
$495.00/1G

References
211108-48-4 Synthesis
tert-Butyl 4-[(Trimethylsilanyl)oxy]-3,6-dihydro-2H-pyridine-1-carboxylate

211108-48-4
35 suppliers
$200.00/1g

tert-butyl (3S,4S)-3-fluoro-4-hydroxypiperidine-1-carboxylate

1174020-44-0
61 suppliers
$180.00/250mg

trans-tert-butyl 3-fluoro-4-hydroxypiperidine-1-carboxylate

1174020-43-9
52 suppliers
$495.00/1G

References

tert-butyl (3S,4S)-3-fluoro-4-hydroxypiperidine-1-carboxylate Related Search:

tert-butyl (3S,4R)-3-fluoro-4-hydroxypiperidine-1-carboxylate