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1191094-23-1

ETHYL 4-CYCLOPROPYL-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLATE synthesis

1synthesis methods
24922-02-9 Synthesis
3-CYCLOPROPYL-3-OXO-PROPIONIC ACID ETHYL ESTER

24922-02-9
209 suppliers
$5.00/1g

ETHYL 4-CYCLOPROPYL-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLATE

1191094-23-1
6 suppliers
$830.00/1g

-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 1,4-dioxane / 4 h / 20 - 100 °C
2: sodium acetate / N,N-dimethyl-formamide / 2 h / 20 - 80 °C

References:

Goldberg, Frederick W.;Leach, Andrew G.;Scott, James S.;Snelson, Wendy L.;Groombridge, Sam D.;Donald, Craig S.;Bennett, Stuart N.L.;Bodin, Cristian;Gutierrez, Pablo Morentin;Gyte, Amy C. [Journal of Medicinal Chemistry,2012,vol. 55,# 23,p. 10652 - 10661]