ChemicalBook CAS DataBase List 1,3-Bis(2,6-dibenzhydryl-4-methylphenyl)-1H-imidazol-3-ium chloride

1,3-Bis(2,6-dibenzhydryl-4-methylphenyl)-1H-imidazol-3-ium chloride synthesis

2synthesis methods

Product Name: 1,3-Bis(2,6-dibenzhydryl-4-methylphenyl)-1H-imidazol-3-ium chloride
CAS Number:1218778-19-8
Molecular formula:C69H57ClN2
Molecular Weight:949.68

(1E,2E)-N1,N2-bis(2,6-bis(diphenylmethyl)-4-methylphenyl)ethane-1,2-diimine (6.14 g, 6.81 mmol) in THF (235 mL) was added to paraformaldehyde (204 mg, 6.81 mmol), anhydrous zinc chloride (928 mg, 6.81 mmol) at 70 °C. After that, HCl in dioxane (4 M, 2.56 mL,10.2 mmol) was added dropwise. After 5 h, at 70 °C, the mixture was concentrated under reduced pressure followed by flash column chromatography over silica gel with CH2Cl2-MeOH (9:1) to give the pale pink solid, which was further purified recrystallization (CH2Cl2-n-hexane) gave 1,3-Bis(2,6-dibenzhydryl-4-methylphenyl)-1H-imidazol-3-ium chloride. N,N'-bis(2,6-bis(diphenylmethyl)-4-methylphenyl)imidazolium chloride

N,N'-bis(2,6-bis(diphenylmethyl)-4-methylphenyl)imidazolium chloride

56138-96-6 Synthesis

56138-96-6
24 suppliers
inquiry

1,3-Bis(2,6-dibenzhydryl-4-methylphenyl)-1H-imidazol-3-ium chloride

1218778-19-8
20 suppliers
inquiry

Yield:-

Steps:

Multi-step reaction with 2 steps
1: magnesium sulfate; formic acid / water; dichloromethane / 96 h / 20 °C
2: zinc(II) chloride; hydrogenchloride / tetrahydrofuran; 1,4-dioxane / 3 h / 70 °C

References:

Chartoire, Anthony;Claver, Carmen;Corpet, Martin;Krinsky, Jamin;Mayen, Julie;Nelson, David;Nolan, Steven P.;Pen Afiel, Itziar;Woodward, Robert;Meadows, Rebecca E. [Organic Process Research and Development,2016,vol. 20,# 2,p. 551 - 557]

106-49-0
409 suppliers
$5.00/5G

1218778-19-8
20 suppliers
inquiry

References

1,3-Bis(2,6-dibenzhydryl-4-methylphenyl)-1H-imidazol-3-ium chloride Related Search:

Phenethyl alcohol

HomePage | About Us | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Product Catalog | Links | Privacy | Terms | Product Manufacturers | New Products
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.