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5-Methyl-3-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1,2,4-oxadiazole synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: sodium sulfate / tetrahydrofuran / 12 h / 25 °C / Inert atmosphere
2: N-ethyl-N,N-diisopropylamine; hydroxylamine hydrochloride / ethanol / 3 h / 25 °C / Reflux; Inert atmosphere
3: 3 h / Reflux; Inert atmosphere

References:

WO2017/37146,2017,A1