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ChemicalBook CAS DataBase List 4-(4-(Prop-2-yn-1-yloxy)phenyl)-1,2,4-triazolidine-3,5-dione
1313211-51-6

4-(4-(Prop-2-yn-1-yloxy)phenyl)-1,2,4-triazolidine-3,5-dione synthesis

7synthesis methods
-

Yield:1313211-51-6 47%

Reaction Conditions:

Stage #1: ethylhydrazine carboxylatewith 1,1'-carbonyldiimidazole in tetrahydrofuran at 23; for 2 h;
Stage #2: 4-(prop-2-ynyloxy)anilinewith triethylamine in tetrahydrofuran at 45; for 3 h;

References:

Naik, Anu;Alzeer, Jawad;Triemer, Therese;Bujalska, Anna;Luedtke, Nathan W. [Angewandte Chemie - International Edition,2017,vol. 56,# 36,p. 10850 - 10853][Angew. Chem.,2017,vol. 129,# 36,p. 10990 - 10993,4] Location in patent:supporting information