Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

N-(3-tert-butyl-1-Methyl-1H-pyrazol-5-yl)-4-(3-fluoro-4-(4-Methyl-1H-iMidazol-1-yl)phenyl)thiazol-2-aMine synthesis

4synthesis methods
118430-73-2 Synthesis
5-AMINO-3-TERT-BUTYL-1-METHYLPYRAZOLE

118430-73-2
94 suppliers
$15.00/1g

N-(3-tert-butyl-1-Methyl-1H-pyrazol-5-yl)-4-(3-fluoro-4-(4-Methyl-1H-iMidazol-1-yl)phenyl)thiazol-2-aMine

1353570-18-9
1 suppliers
inquiry

-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: acetone / 2 h / 60 °C / Inert atmosphere
2: potassium carbonate / methanol / 4 h / 25 °C / Inert atmosphere
3: ethanol / 18.25 h / 25 °C / Reflux; Inert atmosphere

References:

Rynearson, Kevin D.;Buckle, Ronald N.;Barnes, Keith D.;Herr, R. Jason;Mayhew, Nicholas J.;Paquette, William D.;Sakwa, Samuel A.;Nguyen, Phuong D.;Johnson, Graham;Tanzi, Rudolph E.;Wagner, Steven L. [Bioorganic and Medicinal Chemistry Letters,2016,vol. 26,# 16,p. 3928 - 3937]