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18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide

1H-Pyrazol-5-amine, 4-(2-bromo-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl- synthesis

8synthesis methods
363-51-9 Synthesis
2-Chloro-6-fluoroaniline

363-51-9
225 suppliers
$6.00/1g

1H-Pyrazol-5-amine, 4-(2-bromo-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl-

1362477-26-6
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-

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: N,N-dimethyl-formamide / 2 h / Reflux
2.1: potassium tert-butylate / tetrahydrofuran / 1 h / 0 °C
2.2: -10 °C
3.1: acetic acid / water; tetrahydrofuran / 6 h / Reflux

References:

WO2012/31061,2012,A2

61150-58-1 Synthesis
2-BROMO-4-FLUOROPHENYLACETONITRILE

61150-58-1
78 suppliers
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1H-Pyrazol-5-amine, 4-(2-bromo-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl-

1362477-26-6
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References
1-(2-bromo-4-fluorophenyl)propan-2-one

1250021-16-9
10 suppliers
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1H-Pyrazol-5-amine, 4-(2-bromo-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl-

1362477-26-6
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References
899806-25-8 Synthesis
2-Chloro-6-fluorophenylisothiocyanate

899806-25-8
48 suppliers
$75.00/1g

1H-Pyrazol-5-amine, 4-(2-bromo-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl-

1362477-26-6
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References
1003-98-1 Synthesis
2-Bromo-4-fluoroaniline

1003-98-1
389 suppliers
$5.00/5g

1H-Pyrazol-5-amine, 4-(2-bromo-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl-

1362477-26-6
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References