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1401728-63-9

3-(4-bromobenzyl)-2-ethyl-5,7-dimethylpyrazolo[1,5-a]pyrimidine synthesis

3synthesis methods
4-(4-bromobenzyl)-5-ethyl-1H-pyrazol-3-amine

1401728-62-8
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3-(4-bromobenzyl)-2-ethyl-5,7-dimethylpyrazolo[1,5-a]pyrimidine

1401728-63-9
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Yield:1401728-63-9 9.5 g

Reaction Conditions:

with trifluoroacetic acid in 1,4-dioxane at 100; for 16 h;Inert atmosphere;

References:

Velcicky, Juraj;Miltz, Wolfgang;Oberhauser, Berndt;Orain, David;Vaupel, Andrea;Weigand, Klaus;Dawson King, Janet;Littlewood-Evans, Amanda;Nash, Mark;Feifel, Roland;Loetscher, Pius [Journal of Medicinal Chemistry,2017,vol. 60,# 9,p. 3672 - 3683] Location in patent:supporting information