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4-OXO-4-([3-(TRIFLUOROMETHYL)PHENYL]AMINO)BUTANOIC ACID synthesis

1synthesis methods
-

Yield:15386-93-3 85%

Reaction Conditions:

with acetic acid at 20;

Steps:

Synthesis of ligand (HL).

Solution of succinic anhydride (1 mmol) in glacial acetic acid (100 mL)was mixed with a solution of 3-(triflouromethyl)benzeneamine (1 mmol) in glacial acetic acid (80 mL).The reaction mixture was magnetically stirred at room temperature for 6-8 h. The precipitates formed were filtered off and washed with distilled water (400 mL).

References:

Javed;Ali;Shahzadi;Sharma;Qanungo;Munawar;Khan [Russian Journal of General Chemistry,2017,vol. 87,# 10,p. 2409 - 2420][Zh. Obshch. Khim.,2017,vol. 87,# 10,p. 2409 - 2420,12]