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Tetrahydro-pyridazine-1-carboxylic acid tert-butyl ester synthesis

3synthesis methods
154972-38-0 Synthesis
1-benzyl 2-(tert-butyl) tetrahydro-1,2-pyridazinedicarboxylate

154972-38-0
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Tetrahydro-pyridazine-1-carboxylic acid tert-butyl ester

154972-37-9
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Yield:154972-37-9 98%

Reaction Conditions:

with hydrogen;palladium on activated charcoal in methanol at 20; under 760 Torr; for 3 h;

References:

Toya, Tetsuya;Yamaguchi, Kentaro;Endo, Yasuyuki [Bioorganic and Medicinal Chemistry,2002,vol. 10,# 4,p. 953 - 961]