N2-iso-Butyroyl-5'-(4,4'-dimethoxytrityl)-2'-O-propargylguanosine synthesis

2synthesis methods

Product Name:N2-iso-Butyroyl-5'-(4,4'-dimethoxytrityl)-2'-O-propargylguanosine
CAS Number:171486-53-6
Molecular formula:C38H39N5O8
Molecular Weight:693.7449

624-65-7 Synthesis

624-65-7
366 suppliers
$26.00/5mL

81246-83-5
68 suppliers
$70.00/2g

Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-3'-O-2-propyn-1-yl-

171486-57-0
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N2-iso-Butyroyl-5'-(4,4'-dimethoxytrityl)-2'-O-propargylguanosine

171486-53-6
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Yield:171486-53-6 55% ，171486-57-0 22%

Reaction Conditions:

with tetra-(n-butyl)ammonium iodide;di(n-butyl)tin oxide in acetonitrile;benzene at 100;Inert atmosphere;Microwave irradiation;Sealed bottle;

References:

Yamada, Takeshi;Peng, Chang Geng;Matsuda, Shigeo;Addepalli, Haripriya;Jayaprakash, K. Narayanannair;Alam, Md. Rowshon;Mills, Kathy;Maier, Martin A.;Charisse, Klaus;Sekine, Mitsuo;Manoharan, Muthiah;Rajeev, Kallanthottathil G. [Journal of Organic Chemistry,2011,vol. 76,# 5,p. 1198 - 1211] Location in patent:supporting information; experimental part

81246-83-5
68 suppliers
$70.00/2g

106-96-7 Synthesis

106-96-7
330 suppliers
$32.00/25g

171486-53-6
13 suppliers
inquiry

References