1H-1,2,3-Triazole-4-carboxamide,5-amino-1-phenyl- synthesis
- Product Name:1H-1,2,3-Triazole-4-carboxamide,5-amino-1-phenyl-
- CAS Number:20317-25-3
- Molecular formula:C9H9N5O
- Molecular Weight:203.2
622-37-7
45 suppliers
$45.00/100mg
107-91-5
574 suppliers
$5.00/10g
20317-25-3
12 suppliers
$45.00/25mg
Yield:20317-25-3 56%
Reaction Conditions:
with potassium carbonate in dimethyl sulfoxide at 25; for 3 h;Reagent/catalyst;Solvent;Temperature;
Steps:
1-(5-Methyl-1-phenyl-1,2,3-triazol-4-yl)ethan-1-one (3).
General procedure: Phenyl azide (2), 1.19 g (0.01 mol), was added to a solution of 1 g (0.01 mol) of acetylacetone (1) and 1.38 g (0.01 mol) of K2CO3 in 10 mL of DMSO. The mixture was stirred for 3 h at 25°C and poured into ice water, and the precipitate was filtered off and recrystallized. Yield 1.7 g (85%), whitepowder, mp 98°C (from EtOH).
References:
Golobokova, T. V.;Kizhnyaev, V. N.;Proidakov, A. G. [Russian Journal of Organic Chemistry,2020,vol. 56,# 3,p. 446 - 453][Zh. Org. Khim.,2020,vol. 56,# 3,p. 442 - 450,9]
62-53-3
691 suppliers
$10.00/1g
20317-25-3
12 suppliers
$45.00/25mg