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1H-Indole, 2-ethyl-1-methyl-5-nitro- synthesis

3synthesis methods
N-methyl-2-ethylindole

65136-45-0
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1H-Indole, 2-ethyl-1-methyl-5-nitro-

174274-83-0
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Yield:174274-83-0 38%

Reaction Conditions:

with sodium nitrate;sulfuric acid1.) 0 deg C, 5 h, 2.) RT, 12 h;

References:

Kuyper, Lee F.;Baccanari, David P.;Jones, Michael L.;Hunter, Robert N.;Tansik, Robert L.;Joyner, Suzanne S.;Boytos, Christine M.;Rudolph, Sharon K.;Knick, Vince;Wilson, H. Robert;Caddell, J. Marc;Friedman, Henry S.;Comley, John C. W.;Stables, Jeremy N. [Journal of Medicinal Chemistry,1996,vol. 39,# 4,p. 892 - 903]