2-Iodoaniline
- CAS No.
- 615-43-0
- Chemical Name:
- 2-Iodoaniline
- Synonyms
- O-IODOANILINE;2-lodoaniline;Aniline o-iodine;2-IodoaniL;2-Iodylamine;2-IODOANILINE;Aniline, 2-iodo-;Aniline, o-iodo-;2-Iodoaniline>2-iodo-benzenamin
- CBNumber:
- CB5125267
- Molecular Formula:
- C6H6IN
- Molecular Weight:
- 219.02
- MDL Number:
- MFCD00007680
- MOL File:
- 615-43-0.mol
- MSDS File:
- SDS
Melting point | 55-58 °C (lit.) |
---|---|
Boiling point | 262.0±23.0 °C(Predicted) |
Density | 1.8155 (estimate) |
Flash point | >230 °F |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | soluble in Chloroform, DCM, Ethyl Acetate, Toluene |
form | Crystalline Needles |
pka | 2.6(at 25℃) |
color | Yellow to brown |
Water Solubility | Insoluble in water. |
Sensitive | Light Sensitive |
BRN | 2204899 |
InChIKey | UBPDKIDWEADHPP-UHFFFAOYSA-N |
CAS DataBase Reference | 615-43-0(CAS DataBase Reference) |
NIST Chemistry Reference | Benzenamine, 2-iodo-(615-43-0) |
EPA Substance Registry System | o-Iodoaniline (615-43-0) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xn,Xi | |||||||||
Risk Statements | 20/21/22-37/38-36/37/38 | |||||||||
Safety Statements | 36/37-36/37/39-26-36 | |||||||||
RIDADR | 2811 | |||||||||
WGK Germany | 3 | |||||||||
F | 8 | |||||||||
Hazard Note | Irritant | |||||||||
TSCA | T | |||||||||
HazardClass | 6.1(b) | |||||||||
PackingGroup | III | |||||||||
HS Code | 29214210 | |||||||||
NFPA 704 |
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2-Iodoaniline price More Price(47)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | I7004 | 2-Iodoaniline 98% | 615-43-0 | 5g | $50.2 | 2024-03-01 | Buy |
Sigma-Aldrich | I7004 | 2-Iodoaniline 98% | 615-43-0 | 25g | $123 | 2024-03-01 | Buy |
TCI Chemical | I0046 | 2-Iodoaniline | 615-43-0 | 5G | $36 | 2024-03-01 | Buy |
TCI Chemical | I0046 | 2-Iodoaniline | 615-43-0 | 25G | $101 | 2024-03-01 | Buy |
Alfa Aesar | A13059 | 2-Iodoaniline, 98+% | 615-43-0 | 5g | $37.65 | 2024-03-01 | Buy |
2-Iodoaniline Chemical Properties,Uses,Production
Chemical Properties
YELLOW TO BROWN CRYSTALLINE NEEDLES
Uses
2-Iodoaniline is used as an intermediate in organic synthesis.
Uses
2-Iodobenzenamine is an synthetic intermediate for the synthesis of complex organic compounds and pharmaceuticals.
Preparation
2-iodoaniline and its derivatives are commonly used for the preparation of indole-based anticancer drugs, which have high market value, and further synthesis can lead to high-end synthetic intermediates with complex structures.
Take a reaction tube, add 50mg of sodium azide, 75mg of 1-(2-iodophenyl)ethanol, 300uL of trifluoroacetic acid, 150uL of methanesulfonic acid and 1.0mL of hexane, and stir for 24 hours at 40℃. After the reaction, 10 mL of sodium hydroxide solution was added to quench the reaction. The organic phase was washed with 5 mL of brine, and the organic phase was combined and separated by column chromatography to obtain 58.4 mg of 2-iodoaniline in 89% yield.
Synthesis of 2-iodoaniline
Purification Methods
Distil 2-iodoaniline with steam and crystallise it from *benzene/pet ether. The N-acetyl derivative has m 110o. [Beilstein 12 IV 1542.]
2-Iodoaniline Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Dalian Richfortune Chemicals Co., Ltd | 0411-84820922 8613904096939 | sales@richfortunechem.com | China | 304 | 57 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12446 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20293 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18629 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21667 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2136 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10311 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8820 | 58 |
View Lastest Price from 2-Iodoaniline manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-04-27 | 2-Iodoaniline
615-43-0
|
US $5.00 / kg | 1kg | 99.92% | 50000tons | Ouhuang Engineering Materials (Hubei) Co., Ltd | ||
2023-12-24 | 2-Iodoaniline
615-43-0
|
US $100.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | ||
2023-08-29 | 2-Iodoaniline
615-43-0
|
US $10.00 / kg | 100kg | 99% | 10000kgs | Dalian Richfortune Chemicals Co., Ltd |
- 2-Iodoaniline
615-43-0
- US $5.00 / kg
- 99.92%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
- 2-Iodoaniline
615-43-0
- US $100.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
- 2-Iodoaniline
615-43-0
- US $10.00 / kg
- 99%
- Dalian Richfortune Chemicals Co., Ltd