1H-Indole-7-carbonitrile,1-methyl- synthesis

2synthesis methods

96631-87-7 Synthesis

Yield:52951-14-1 80%

Reaction Conditions:

Stage #1: 1H-indole-7-carbonitrilewith sodium hydride in acetonitrile at 0; for 0.5 h;
Stage #2: methyl iodide in acetonitrile at 0 - 20; for 16 h;

References:

Ciszewski, Lukasz W.;Durka, Jakub;Gryko, Dorota [Organic Letters,2019,vol. 21,# 17,p. 7028 - 7032] Location in patent:supporting information

280752-68-3 Synthesis

1H-Indole-7-carbonitrile,1-methyl- Related Search:

7-CYANOINDOLE

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