1H-Pyrrolo[2,3-c]pyridine-5-carboxylicacid(9CI) synthesis
- Product Name:1H-Pyrrolo[2,3-c]pyridine-5-carboxylicacid(9CI)
- CAS Number:130473-27-7
- Molecular formula:C8H6N2O2
- Molecular Weight:162.15
108-47-4
230 suppliers
$9.00/1g
130473-27-7
54 suppliers
$80.00/100mg
Yield:-
Steps:
Multi-step reaction with 5 steps
1.1: H2SO4; KNO3 / 12 h / 0 - 130 °C
1.2: 2.5 g / benzeneselenic anhydride / dioxane / 10 h / Heating
2.1: 90 percent / p-toluenesulfonic acid / toluene / 2 h / Heating
3.1: 69 percent / dimethylformamide / 3 h / 90 °C
4.1: p-toluenesulfonic acid / acetonitrile; H2O / 5 h / Heating
5.1: HCO2H; aq. H2O2 / 0 - 5 °C
References:
Wishka, Donn G.;Walker, Daniel P.;Yates, Karen M.;Reitz, Steven C.;Jia, Shaojuan;Myers, Jason K.;Olson, Kirk L.;Jacobsen, E. Jon;Wolfe, Mark L.;Groppi, Vincent E.;Hanchar, Alexander J.;Thornburgh, Bruce A.;Cortes-Burgos, Luz A.;Wong, Erik H. F.;Staton, Brian A.;Raub, Thomas J.;Higdon, Nicole R.;Wall, Theron M.;Hurst, Raymond S.;Walters, Rodney R.;Hoffmann, William E.;Hajos, Mihaly;Franklin, Stanley;Carey, Galen;Gold, Lisa H.;Cook, Karen K.;Sands, Steven B.;Zhao, Sabrina X.;Soglia, John R.;Kalgutkar, Amit S.;Arneric, Stephen P.;Rogers, Bruce N. [Journal of Medicinal Chemistry,2006,vol. 49,# 14,p. 4425 - 4436]
![1H-Pyrrolo[2,3-c]pyridine-5-carboxaldehyde (9CI)](/CAS/GIF/130473-26-6.gif)
130473-26-6
77 suppliers
$180.00/250mg
130473-27-7
54 suppliers
$80.00/100mg
119694-70-1
4 suppliers
inquiry
130473-27-7
54 suppliers
$80.00/100mg
![1H-Pyrrolo[2,3-c]pyridine, 5-(1,3-dioxolan-2-yl)-](/CAS/GIF/130473-24-4.gif)
130473-24-4
0 suppliers
inquiry
130473-27-7
54 suppliers
$80.00/100mg
5832-38-2
12 suppliers
inquiry
130473-27-7
54 suppliers
$80.00/100mg