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178460-78-1

(1S)-2-chloro-1-(4-chlorophenyl)ethan-1-ol synthesis

6synthesis methods
-

Yield:178460-78-1 99%

Reaction Conditions:

with bis(1,5-cyclooctadiene)diiridium(I) dichloride;f-amphox;hydrogen;potassium carbonate in ethanol;hexane at 25 - 30; under 38002.6 Torr; for 4 h;Inert atmosphere;Glovebox;Autoclave;enantioselective reaction;

References:

Yin, Congcong;Wu, Weilong;Hu, Yang;Tan, Xuefeng;You, Cai;Liu, Yuanhua;Chen, Ziyi;Dong, Xiu-Qin;Zhang, Xumu [Advanced Synthesis and Catalysis,2018,vol. 360,# 11,p. 2119 - 2124] Location in patent:supporting information