2-(2-IMIDAZOL-1-YL-ETHYL)-ISOINDOLE-1,3-DIONE synthesis
- Product Name:2-(2-IMIDAZOL-1-YL-ETHYL)-ISOINDOLE-1,3-DIONE
- CAS Number:72459-53-1
- Molecular formula:C13H11N3O2
- Molecular Weight:241.25
Yield:72459-53-1 75%
Reaction Conditions:
Stage #1: 1H-imidazolewith sodium hydride in N,N-dimethyl-formamide;
Stage #2: 2-(2-bromoethyl)isoindoline-1,3-dione in N,N-dimethyl-formamide at 100; for 8 h;
References:
Buchholz, Mirko;Heiser, Ulrich;Schilling, Stephan;Niestroj, André J.;Zunkel, Katrin;Demuth, Hans-Ulrich [Journal of Medicinal Chemistry,2006,vol. 49,# 2,p. 664 - 677]
574-98-1
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72459-53-1
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