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ChemicalBook CAS DataBase List 2-(4-CHLORO-PHENOXY)-1-PIPERAZIN-1-YL-ETHANONE
143999-83-1

2-(4-CHLORO-PHENOXY)-1-PIPERAZIN-1-YL-ETHANONE synthesis

8synthesis methods
-

Yield:143999-83-1 91%

Reaction Conditions:

Stage #1: 4-Chlorophenoxyacetic acidwith N-Bromosuccinimide;triphenylphosphine in dichloromethane at 0 - 5; for 0.25 h;
Stage #2: piperazinewith pyridine in dichloromethane at 20; for 0.75 h;

References:

Bandgar;Bettigeri [Synthetic Communications,2004,vol. 34,# 16,p. 2917 - 2924]

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