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397-53-5

2-(4-FLUOROPHENYL)IMIDAZO[1,2-A]PYRIMIDINE synthesis

4synthesis methods
-

Yield:397-53-5 85%

Reaction Conditions:

Stage #1: 1-(4-Fluorophenyl)ethanonewith [Hydroxy(tosyloxy)iodo]benzene;N-butylpyridinium tetrafluoroborateHeating;
Stage #2: 2-aminopyrimidinewith sodium carbonate;N-butylpyridinium tetrafluoroborate at 20;

References:

Xie, Yuan-Yuan [Synthetic Communications,2005,vol. 35,# 13,p. 1741 - 1746]

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