2-(4-Iodophenyl)-1-phenyl-1H-benzimidazole synthesis
- Product Name:2-(4-Iodophenyl)-1-phenyl-1H-benzimidazole
- CAS Number:760212-42-8
- Molecular formula:C19H13IN2
- Molecular Weight:396.22
624-38-4
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760212-42-8
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Yield:760212-42-8 62%
Reaction Conditions:
with potassium fluoride in dimethyl sulfoxide at 130;
Steps:
2.2-2 Synthesis of Intermediate 2-2
Intermediate 2-1 (9.3 g, 0.029 mol),1,4-diiodobenzene (9.6 g, 0.029 mol),Catalyst Copper (II) (0.52 g, 0.0029 mol),Potassium fluoride (1.7 g, 0.029 mol) was addedDMSO 370 mlAnd the reaction was carried out at 130 ° C.After cooling the reaction mixture, the crude product was added by the amount of the reaction solvent, and after the extraction, column purification (n-Hexane: methylene chloride) was conducted to obtain 7.1 g (yield: 62%) of Intermediate 2-2.
References:
KR101527181,2015,B1 Location in patent:Paragraph 0129; 0130; 0131
![Benzamide, 4-iodo-N-[2-(phenylamino)phenyl]-](/CAS/20210305/GIF/760212-43-9.gif)
760212-43-9
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760212-42-8
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$95.00/200mg
1711-02-0
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534-85-0
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760212-42-8
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2622-60-8
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760212-42-8
23 suppliers
$95.00/200mg