ChemicalBook CAS DataBase List 2-(5-TERT-BUTYL-2-HYDROXYPHENYL)BENZOTRIAZOLE

2-(5-TERT-BUTYL-2-HYDROXYPHENYL)BENZOTRIAZOLE synthesis

10synthesis methods

Product Name:2-(5-TERT-BUTYL-2-HYDROXYPHENYL)BENZOTRIAZOLE
CAS Number:3147-76-0
Molecular formula:C16H17N3O
Molecular Weight:267.33

Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

1000210-73-0
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2-(5-TERT-BUTYL-2-HYDROXYPHENYL)BENZOTRIAZOLE

3147-76-0
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$52.00/25g

Yield: 59%

Reaction Conditions:

with sulfuric acid;zinc in water;toluene at 60 - 80; for 4 h;

Steps:

1
A ball condenser, a thermometer, and a stirrer were attached to a 300 ml four-necked flask, and 2- (5-tert-butyl-2-hydroxyphenyl) -2H-benzotriazole N-38.2 g (0.135 mol),75 g of toluene, 50 ml of water and 10.9 g (0.167 mol) of zinc powder were charged, 30.3 g (0.193 mol) of 62.5% sulfuric acid was added dropwise at 60 to 70 ° C. over 2 hours, And the mixture was stirred at 80 ° C. for 2 hours. The lower aqueous layer was removed by liquid separation at 75 to 80 ° C, 20 ml of water was added, and the lower aqueous layer was separated and removed at 75 to 80 ° C. Toluene was recovered under reduced pressure, 70 ml of isopropyl alcohol added. After cooling to 20 ° C., the precipitated crystals were filtered, washed and dried,2- (5-tert-butyl-2-hydroxyphenyl) -2H-benzotriazole was reacted with31.5 g were obtained. Yield 59% (from ortho-nitroaniline).

References:

Shipro Kasei Co., Ltd.;Shin-Nakamura Chemical Co., Ltd.;Public university corporation osaka prefecture University;Uesaka, Toshiyuki;Ishitani, Tomoyuki;Fujiwara, Takafumi;Yoshida, Shojiro;Shimeno, Takahito;Nakazumi, Hiroyuki;Maeda, Takeshi JP2018/158912, 2018, A Location in patent:Paragraph 0027; 0030