2,7-Dihydroxy-9-fluorenone synthesis
- Product Name:2,7-Dihydroxy-9-fluorenone
- CAS Number:42523-29-5
- Molecular formula:C13H8O3
- Molecular Weight:212.2
14348-75-5
307 suppliers
$14.00/1g
42523-29-5
248 suppliers
$6.00/1g
Yield:42523-29-5 865 mg
Reaction Conditions:
with lithium hydroxide monohydrate;N1,N2-bis(4-hydroxy-2,6-dimethylphenyl)oxalamide;copper(II) acetylacetonate in water;dimethyl sulfoxide at 120; for 4 h;
Steps:
4 Synthesis of 2,7-dihydroxyfluoren-9-one using bis (2,4-pentanedionato) copper (II)
2,7-dibromofluoren-9-one (manufactured by Tokyo Chemical Industry Co., Ltd., 1.35 g, 4.0 mmol),Lithium hydroxide monohydrate (704 mg, 16.8 mmol),Bis (2,4-pentanedionato) copper (II) (53.6 mg, 0.20 mmol),A mixture of N, N'-bis (2,6-dimethyl-4-hydroxyphenyl) oxamide (65.0 mg, 0.20 mmol) and DMSO / water (9.6 mL / 2.4 mL) at 120 ° C. for 4 hours Heated and stirred. After cooling to room temperature, the reaction mixture is diluted with waterFurthermore, 3 M hydrochloric acid is added to adjust the pH to acidic,The resulting red solid was collected by filtration and vacuum dried (100 ° C., overnight).The target 2,7-dihydroxyfluoren-9-one was obtained as a red solid (865 mg, quantitative, HPLC purity: 85.6%).
References:
JP2019/77634,2019,A Location in patent:Paragraph 0106-0108
![[1,1'-Biphenyl]-2-carboxylic acid, 4,4'-dihydroxy-, methyl ester](/CAS/20200611/GIF/765944-63-6.gif)
765944-63-6
0 suppliers
inquiry
42523-29-5
248 suppliers
$6.00/1g
202865-84-7
29 suppliers
$67.00/250mg
100-83-4
610 suppliers
$5.00/10g
42523-29-5
248 suppliers
$6.00/1g
53197-57-2
36 suppliers
$378.00/1g
42523-29-5
248 suppliers
$6.00/1g
42523-28-4
0 suppliers
inquiry
42523-29-5
248 suppliers
$6.00/1g