(+/-)-2-ACETOXYPROPIONIC ACID synthesis
- Product Name:(+/-)-2-ACETOXYPROPIONIC ACID
- CAS Number:535-17-1
- Molecular formula:C5H8O4
- Molecular Weight:132.11
Yield:535-17-1 100%
Reaction Conditions:
with sulfuric acid in water at 0 - 100; for 0.5 h;Temperature;Reagent/catalyst;Solvent;
Steps:
1-6; 8; 9 Example 3
Step 1): small-scale preparation of acetolactate catalyzed by sulfuric acid--Similar to Example 1, 200 g of lactic acid (85% aqueous solution, 1.00 equivalent) and 5 mL of concentrated sulfuric acid were added to a 1L three-necked flask, and the reaction was mechanically stirred to reduce the reaction to 0 to 10 ° C. 360 g (1.90 equivalent) of acetic anhydride was added dropwise. 30min. After the dropwise addition, the reaction solution was transferred to a 1L single-necked flask. The temperature was slowly raised to 90-100 ° C and concentrated under reduced pressure until the weight of the residue was about 270g. The acetolactate (containing sulfuric acid) was obtained. Used directly in the next reaction.
References:
CN110386878,2019,A Location in patent:Paragraph 0031-0044; 0047-0050
849585-22-4
1 suppliers
inquiry
64-19-7
1586 suppliers
$10.00/25ML
535-17-1
46 suppliers
$63.00/1g
802294-64-0
1 suppliers
inquiry
