2-AMINO-N-CYCLOPROPYLBENZAMIDE synthesis
- Product Name:2-AMINO-N-CYCLOPROPYLBENZAMIDE
- CAS Number:30510-67-9
- Molecular formula:C10H12N2O
- Molecular Weight:176.22
765-30-0
503 suppliers
$10.00/25g
552-89-6
646 suppliers
$5.00/1g
30510-67-9
34 suppliers
$45.00/50mg
Yield:30510-67-9 64%
Reaction Conditions:
with glacial acetic acid in ethyl acetate;propan-2-one at 20; for 16 h;UV-irradiation;Green chemistry;
Steps:
2-Aminobenzamides 4-6; General Procedure
General procedure: A mixture of 2-nitrobenzaldehyde 1 (0.2 mmol, 1.0 equiv), primary amine 2 or 3 (0.8 mmol, 4.0 equiv), acetic acid (19.2 L, 0.4 mmol, 2.0 equiv), and EtOAc/acetone (6:1, 3.0 mL) in a 5-mL glass bottle (equipped with a magnetic stirring bar) at r.t. was irradiated with UV light (24-W, 365-375 nm) for 16 h. Purification was by column chromatography (silica gel).
References:
Zeng, Dishu;Yang, Tianbao;Tang, Niu;Deng, Wei;Xiang, Jiannan;Yin, Shuang-Feng;Kambe, Nobuaki;Qiu, Renhua [Synthesis,2022,vol. 54,# 10,p. 2361 - 2372] Location in patent:supporting information
118-48-9
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$5.00/5G
765-30-0
503 suppliers
$10.00/25g
30510-67-9
34 suppliers
$45.00/50mg
5344-90-1
340 suppliers
$6.00/5g
765-30-0
503 suppliers
$10.00/25g
30510-67-9
34 suppliers
$45.00/50mg
118-92-3
0 suppliers
$25.89/25g
765-30-0
503 suppliers
$10.00/25g
30510-67-9
34 suppliers
$45.00/50mg
88229-20-3
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inquiry
30510-67-9
34 suppliers
$45.00/50mg