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2-CHLORO-6,8-DINITRO-QUINOLINE synthesis

2synthesis methods
296759-27-8 Synthesis
6,8-DINITRO-3,4-DIHYDRO-1H-QUINOLIN-2-ONE

296759-27-8
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2-CHLORO-6,8-DINITRO-QUINOLINE

296759-28-9
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Yield:296759-28-9 98%

Reaction Conditions:

with trichlorophosphate in N,N-dimethyl-formamide at 60; for 4 h;Chlorination;aromatization;

References:

Lee, Byoung Se;Chu, Soyoung;Lee, Byung Chul;Chi, Dae Yoon;Choe, Yearn Seong;Jeong, Kyung Ja;Jin, Changbae [Bioorganic and Medicinal Chemistry Letters,2000,vol. 10,# 14,p. 1559 - 1562]