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ChemicalBook CAS DataBase List 2-chloro-6-(trifluoroMethoxy) quinoline
577967-67-0

2-chloro-6-(trifluoroMethoxy) quinoline synthesis

2synthesis methods
6-(trifluoroMethoxy) quinolin-2(1H)-one

676131-27-4
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2-chloro-6-(trifluoroMethoxy) quinoline

577967-67-0
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Yield:577967-67-0 91%

Reaction Conditions:

with trichlorophosphate at 110;

References:

Knight, Roland L.;Allen, Daniel R.;Birch, Helen L.;Chapman, Gayle A.;Galvin, Frances C.;Jopling, Louise A.;Lock, Christopher J.;Meissner, Johannes W.G.;Owen, David A.;Raphy, Gilles;Watson, Robert J.;Williams, Sophie C. [Bioorganic and Medicinal Chemistry Letters,2008,vol. 18,# 2,p. 629 - 633]