2-CHLORO-N-(3-CHLORO-4-METHYLPHENYL)ACETAMIDE synthesis
- Product Name:2-CHLORO-N-(3-CHLORO-4-METHYLPHENYL)ACETAMIDE
- CAS Number:99585-97-4
- Molecular formula:C9H9Cl2NO
- Molecular Weight:218.08
95-74-9
237 suppliers
$9.00/25g
79-07-2
386 suppliers
$5.00/25g
99585-97-4
22 suppliers
$57.50/250mg
Yield:99585-97-4 67%
Reaction Conditions:
with pyridine in benzene at 20 - 60; for 5 h;
Steps:
2-Haloacetamides 8a-8d and 9a-9d (general procedure)
General procedure: A solution of 0.02 mol of bromo- orchloroacetamide in 40 mL of dry benzene was addedto mixture of 0.02 mol of amine 6a, 6b, or 7a-7c and1.6 g (0.02 mol) of dry pyridine in 70 mL of dry benzeneunder stirring and cooling with ice water. The reactionmixture was stirred at room temperature for 4 h and then1 h at 60°C. After cooling, 30 mL of water was added,the layers were separated, the benzene layer was washedwith water, and the solvent was removed by distillation.The residue was crystallied and recrystallized.
References:
Arustamyan, Zh. S.;Margaryan;Aghekyan;Panosyan;Muradyan;Tumajyan [Russian Journal of Organic Chemistry,2021,vol. 57,# 2,p. 195 - 202][Zh. Org. Khim.,2021,vol. 57,# 2,p. 230 - 238,8]
79-04-9
350 suppliers
$12.00/5g
95-74-9
237 suppliers
$9.00/25g
99585-97-4
22 suppliers
$57.50/250mg
95-74-9
237 suppliers
$9.00/25g
99585-97-4
22 suppliers
$57.50/250mg