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2-CYANO-N-THIAZOL-2-YL-ACETAMIDE synthesis

4synthesis methods
201230-82-2 Synthesis
carbon monoxide

201230-82-2
1 suppliers
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590-17-0 Synthesis
Bromoacetonitrile

590-17-0
323 suppliers
$5.00/5g

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Yield:90158-62-6 88 %

Reaction Conditions:

with palladium diacetate;sodium carbonate;Xantphos in acetonitrile at 50; under 4500.45 Torr;Inert atmosphere;Autoclave;

References:

Bao, Zhi-Peng;Wu, Xiao-Feng [Angewandte Chemie - International Edition,2023,vol. 62,# 19,art. no. E202301671][Angew. Chem.,2023,vol. 135,# 19] Location in patent:supporting information